A heavyweight boxer isn’t the same for both sexes. If you mean coupling heavyweight against featherweight of the other gender or something similar to compensate, it could work but would probably be seen as unfair, it would be hard to draw the line on where it’s equivalent.
I do think it would be interesting to have mixed team sports where a certain number of each gender needs to be on each side, but it would probably end up with positions always being relegated to the same sex.
The problem is that a man in the same weight class as a women would still wipe the floor with them.
I doubt even a heavy weight women against a featherweight man would be fair. Every category would be dominated by men.